The Thanksgiving Day spacewalk started at 12:36 p.m. CST, almost 45 minutes ahead of schedule, and ended officially at 6:46 p.m.
Lopez-Alegria and Herrington were helped by intravehicular officer Paul Lockhart, Endeavour's pilot, who coached them through their activities from the shuttle's aft flight deck. Expedition 5 NASA ISS Science Officer Peggy Whitson, with help from her Expedition 6 successor Don Pettit, operated the station's Canadarm 2. Endeavour Commander Jim Wetherbee did photo and TV documentation.
The first task for Lopez-Alegria, wearing the spacesuit with red stripes, and Herrington, in the all-white spacesuit, was connection of two fluid jumpers between P1 and the Starboard Zero (S0) truss centerpiece. The jumpers link plumbing for ammonia in the station's cooling system. Next the spacewalkers removed the starboard keel pin, a launch support, and using the Crew and Equipment Translation Aid - one of two handcar-like devices on the truss railway - moved it to the proper location and stowed it in the P1 truss structure.
Lopez-Alegria and Herrington installed a second Wireless video system External Transceiver Assembly (WETA), this one on the P1 truss. They had installed the first WETA on the station's Unity Node during their Tuesday spacewalk. After removal and stowage of the port keel pin, they did the first of the additional jobs, releasing launch locks on the P1's radiator beams. Then they turned their attention to relocation of the CETA cart.
Herrington, in a foot restraint on Canadarm2, lifted the cart from its tracks and held it while Whitson swung him and his cargo around the front of the station, past Endeavour's cargo bay and to the Starboard One (S1), where he attached the cart to tracks and secured it to its sister CETA, launched with the S1 truss on Atlantis' STS-112 flight in October. The relocation was done to clear the P1 tracks for the Canadarm2 to move along them on its Mobile Transporter and Mobile Base System.
The CETA move accomplished, the two spacewalkers moved on to the second additional task, reconnection of one of the cables on the WETA installed Tuesday. Both extra jobs took about 20 minutes.
The oxygen prebreathe protocol before today's spacewak to purge nitrogen from spacewalkers' bloodstreams, was done on the shuttle's cycle ergometer. Whitson and Expedition 6 Commander Ken Bowersox checked out the station's cycle ergometer with a newly uplinked procedure to use it in manual mode.
Expedition 5 Commander Valery Korzun, Whitson and Flight Engineer Sergei Treschev continued their handover briefings for Bowersox, cosmonaut Nikolai Budarin and Pettit. Transfer of equipment and supplies between the station and shuttle also continued.
The Carbon Dioxide Removal Assembly (CDRA) is functioning well. Whitson and Bowersox replaced two valves and cleaned airlines on the device on Wednesday, and later that evening they repaired a leak in a CDRA vacuum line.