Decree 316-157 of 4 April 1961 authorised development of a family of solid propellant launch vehicles utilising various combinations of three stages (the RT-2, RT-15, and RT-25). The RT-25 IRBM used the first and third stages of the RT-2 ICBM. M Yu Tsirulnikov at SKB-172 in Perm was responsible for development of the RT-25. However there was little interest in this variant and in 1963 further development was dropped.

Manufacturer: Tsirulnikov. Liftoff Thrust: 892.000 kN (200,529 lbf). Total Mass: 41,000 kg (90,000 lb). Core Diameter: 1.84 m (6.03 ft). Total Length: 16.00 m (52.00 ft). Span: 2.00 m (6.50 ft). Maximum range: 4,500 km (2,700 mi).