Payloads included:

• Orbiter middeck: CEBAS (German/US biological module with fish and snails); dinosaur skull (part of a museum educational program)
• Bay 1: Tunnel Adapter
• Bay 3: Orbiter Docking System/External Airlock
• Bay 4-7: Transfer Tunnel
• Bay 8-12: Spacehab Double Module (payloads included supplies for Mir, X-ray crystallography detector planned for the International Space Station)
• Bay 13P: Getaway Special GABA carrier with G-141, G-145 (German materials processing experiments)
• Bay 13S: Getaway Special GABA carrier with G-093 (University of Michigan fluid dynamics experiment), G-432 (Chinese materials processing experiment)

Despite fits problems with his Sokol emergency spacesuit, Andy Thomas replaced David Wolf as a Mir crew member on January 25. Endeavour undocked from Mir on January 29 at 16:57 GMT and made one flyaround of the station before departing and landing at Kennedy Space Center's runway 15 at 22:35 GMT on January 31. References: 2, 7, 276.

Solovyov handed over command of Mir to EO-25 commander Musabayev, and the Mir EO-24 crew and Eyharts undocked from the forward port of Mir at 05:52 GMT on February 19 aboard the Soyuz TM-26 for their return home. On February 20, the EO-25 crew and Andy Thomas of the NASA-7 mission boarded Soyuz TM-27 and undocked from the Kvant port at 08:48 GMT. They redocked with the forward port on Mir at 09:32 GMT. This freed up the Kvant port for a test redocking of the Progress M-37 cargo ship, parked in a following orbit with Mir during the crew transfer. References: 2, 9,51, 276.